What The Research Shows

LACRIFILL® Canalicular Gel has been cleared for use by the FDA based on the results of clinical studies showing it’s safe for patients and effective at keeping natural tears in the eye.
See Results

Proof-of-Concept Study

A pilot study of LACRIFILL Canalicular Gel involving 63 patients with dry eye found there was an increase in tears remaining on the eye and an increase in tear volume, lasting for at least 3 months.


of patients had no pain


of patients had no infections


reported their eyes felt better

Randomized Non-Inferiority Clinical Trial

The trial randomly assigned patients 2:1 to treatment with either LACRIFILL or Oasis Form Fit. The trial found that:


of eyes demonstrated increased corneal staining.


of patients reported some degree of discomfort during the procedure.